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Nat Rev Mol Cell Biol. 2001 Jan;2(1):21-32.

Mitotic kinases as regulators of cell division and its checkpoints.

Author information

  • Max-Planck-Institute for Biochemistry, Department of Cell Biology, Am Klopferspitz 18a, D-82152 Martinsried, Germany. nigg@biochem.mpg.de

Abstract

Mitosis and cytokinesis are undoubtedly the most spectacular parts of the cell cycle. Errors in the choreography of these processes can lead to aneuploidy or genetic instability, fostering cell death or disease. Here, I give an overview of the many mitotic kinases that regulate cell division and the fidelity of chromosome transmission.

PMID:
11413462
[PubMed - indexed for MEDLINE]
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