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Curr Opin Biotechnol. 2001 Jun;12(3):231-6.

The identification of microorganisms by fluorescence in situ hybridisation.

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  • 1Molecular Ecology Group, Max Planck Institute for Marine Microbiology, Celsiusstrasse 1, D-28359, Bremen, Germany.


Fluorescence in situ hybridisation (FISH) with rRNA-targeted oligonucleotide probes facilitates the rapid and specific identification of individual microbial cells in their natural environments. Over the past year there have been a number of methodological developments in this area and new applications of FISH in microbial ecology and biotechnology have been reported.

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