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News Physiol Sci. 1999 Jun;14:121-125.

Arteriogenesis Versus Angiogenesis: Two Mechanisms of Vessel Growth.

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  • 1Department for Experimental Cardiology of the Max Planck Institute for Physiological and Clinical Research, Benekestrasse 2, D-61231 Bad Nauheim, Germany.


After birth, new blood vessel formation proceeds via angiogenesis or arteriogenesis. Angiogenesis (capillary sprouting) results in higher capillary density. Arteriogenesis (rapid proliferation of collateral arteries) is potentially able to significantly alter the outcome of coronary and peripheral artery disease. The processes share some growth features but differ in many aspects.

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