Send to

Choose Destination
See comment in PubMed Commons below
J Am Chem Soc. 2001 Jun 13;123(23):5396-400.

Regiochemistry in the Pauson-Khand reaction: has a trans effect been overlooked?

Author information

  • 1Universit√© Joseph Fourier de Grenoble, Chimie Recherche (LEDSS), 38041 Grenoble, France.


Alkyne-dicobalt hexacarbonyl complexes have been studied by DFT to examine whether electronic differences in the acetylenic substituents could play a role in determining the regiochemical outcome in the Pauson-Khand reaction. It appears that in some instances the regiochemistry is, in fact, governed exclusively by the electronic nature of the acetylenic substituents through the discriminant loss of a carbon monoxide ligand.

PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Chemical Society
    Loading ...
    Write to the Help Desk