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Nat Rev Neurosci. 2001 Jun;2(6):417-24.

Primate anterior cingulate cortex: where motor control, drive and cognition interface.

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  • 1Department of Neurology and Neurosurgery, McGill University, Montreal Neurological Institute, 3801 University Street, Montreal, Quebec H3A 2B4, Canada. tomas@bic.mni.mcgill.ca


Controversy surrounds the function of the anterior cingulate cortex. Recent discussions about its role in behavioural control have centred on three main issues: its involvement in motor control, its proposed role in cognition and its relationship with the arousal/drive state of the organism. I argue that the overlap of these three domains is key to distinguishing the anterior cingulate cortex from other frontal regions, placing it in a unique position to translate intentions to actions.

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