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Croat Med J. 2001 Jun;42(3):229-32.

Application of low copy number DNA profiling.

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  • 1Forensic Science Service, Trident Court, 2960 Solihull Parkway, Birmingham B37 7YN, UK.


Low copy number (LCN) DNA profiling is a technique sensitive enough to analyze just a few cells. When this kind of analysis is carried out, special considerations are needed to interpret the results. In particular, it is important to consider the implications of allele dropout and the possibility of contamination from a laboratory source. A rationale for interpreting LCN DNA is described.

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