Homologous recombination: from model organisms to ...[Genome Biol. 2001]

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1: Genome Biol. 2001;2(5):REVIEWS1014. Epub 2001 Apr 26. Links

Homologous recombination: from model organisms to human disease.

Modesti M, Kanaar R.

Department of Cell Biology and Genetics, Erasmus University Rotterdam, 3000 DR Rotterdam, The Netherlands.

Recent experiments show that properly controlled recombination between homologous DNA molecules is essential for the maintenance of genome stability and for the prevention of tumorigenesis.

PMID: 11387040 [PubMed - indexed for MEDLINE]

PMCID: PMC138934

ReviewRAD51, genomic stability, and tumorigenesis.
Cancer Lett. 2005 Feb 10; 218(2):127-39.

[Cancer Lett. 2005]
ReviewHomologous repair of DNA damage and tumorigenesis: the BRCA connection.
Oncogene. 2002 Dec 16; 21(58):8981-93.

[Oncogene. 2002]
BRCA2 regulates homologous recombination in response to DNA damage: implications for genome stability and carcinogenesis.
Cancer Res. 2005 May 15; 65(10):4117-25.

[Cancer Res. 2005]
ReviewInteractions between BRCA proteins and DNA structure.
Exp Cell Res. 2001 Mar 10; 264(1):67-73.

[Exp Cell Res. 2001]
BRCA1 regulates RAD51 function in response to DNA damage and suppresses spontaneous sister chromatid replication slippage: implications for sister chromatid cohesion, genome stability, and carcinogenesis.
Cancer Res. 2005 Dec 15; 65(24):11384-91.

[Cancer Res. 2005]
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Cited by 1 PubMed Central article

Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage.
Essers J, Houtsmuller AB, van Veelen L, Paulusma C, Nigg AL, Pastink A, Vermeulen W, Hoeijmakers JH, Kanaar R. EMBO J. 2002 Apr 15; 21(8):2030-7.

[EMBO J. 2002]

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