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Eur J Heart Fail. 2001 Jun;3(3):315-22.

More 'malignant' than cancer? Five-year survival following a first admission for heart failure.

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  • 1Clinical Research Initiative in Heart Failure, University of Glasgow, G12 8QQ, Glasgow, UK.

Abstract

BACKGROUND:

The prognostic impact of heart failure relative to that of 'high-profile' disease states such as cancer, within the whole population, is unknown.

METHODS:

All patients with a first admission to any Scottish hospital in 1991 for heart failure, myocardial infarction or the four most common types of cancer specific to men and women were identified. Five-year survival rates and associated loss of expected life-years were then compared.

RESULTS:

In 1991, 16224 men had an initial hospitalisation for heart failure (n=3241), myocardial infarction (n=6932) or cancer of the lung, large bowel, prostate or bladder (n=6051). Similarly, 14842 women were admitted for heart failure (n=3606), myocardial infarction (n=4916), or cancer of the breast, lung, large bowel or ovary (n=6320). With the exception of lung cancer, heart failure was associated with the poorest 5-year survival rate (approximately 25% for both sexes). On an adjusted basis, heart failure was associated with worse long-term survival than bowel cancer in men (adjusted odds ratio, 0.89; 95% CI, 0.82-0.97; P<0.01) and breast cancer in women (odds ratio, 0.59; 95% CI, 0.55-0.64; P<0.001). The overall population rate of expected life-years lost due to heart failure in men was 6.7 years/1000 and for women 5.1 years/1000.

CONCLUSION:

With the notable exception of lung cancer, heart failure is as 'malignant' as many common types of cancer and is associated with a comparable number of expected life-years lost.

PMID:
11378002
[PubMed - indexed for MEDLINE]
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