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Br J Sports Med. 2001 Jun;35(3):170-3.

The acute phase response and exercise: court and field sports.

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  • 1Department of Sports Medicine, Australian Institute of Sport, Belconnen, ACT, Australia.



To determine the presence or absence of an acute phase response after training for court and field sports.


All members of the Australian women's soccer team (n = 18) and all members of the Australian Institute of Sport netball team (n = 14).


Twelve acute phase reactants (white blood cell count, neutrophil count, platelet count, serum iron, ferritin, and transferrin, percentage transferrin saturation, alpha(1) antitrypsin, caeruloplasmin, alpha(2) acid glycoprotein, C reactive protein, and erythrocyte sedimentation rate) were measured during a rest period and after moderate and heavy training weeks in members of elite netball and women's soccer teams.


Responses consistent with an acute phase response were found in five of 24 tests in the soccer players, and in three of 24 tests in the netball players. Responses in the opposite direction were found in seven of 24 tests in the soccer players and two of 24 tests in the netballers. The most sensitive reactant measured, C reactive protein, did not respond in a manner typical of an acute phase response.


An acute phase response does not seem to occur as a consequence of the levels of training typical of elite female netball and soccer teams. This has implications for the interpretation of biochemical variables in these groups.

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