J Nat Prod. 2001 May;64(5):588-91.

Phenylnaphthalene compounds from the subterranean part of Vitex rotundifolia and their antibacterial activity against methicillin-resistant Staphylococcus aureus.

Kawazoe K, Yutani A, Tamemoto K, Yuasa S, Shibata H, Higuti T, Takaishi Y.

Source

Faculty of Pharmaceutical Sciences, The University of Tokushima, Tokushima, 770-8505, Japan. kawazoe@ph2.tohushima-u.ac.jp

Abstract

A careful investigation of the subterranean part of Vitex rotundifolia has shown that this plant contains five novel lignans having a 1-phenylnaphthalene-type skeleton together with four known lignans. These structures were elucidated on the basis of spectroscopic data. Furthermore, some of the isolated compounds showed antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA).

PMID:: 11374949; [PubMed - indexed for MEDLINE]

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