J Mol Microbiol Biotechnol. 2001 Jul;3(3):329-46.

The complete phosphotransferase system in Escherichia coli.

Tchieu JH, Norris V, Edwards JS, Saier MH Jr.

Source

Department of Biology, University of California at San Diego, La Jolla 92093-0116, USA.

Abstract

We here tabulate and describe all currently recognized proteins of the phosphoenolpyruvate:sugar phosphotransferase system (PTS) and their homologues encoded within the genomes of sequenced E. coli strains. There are five recognized Enzyme I homologues and six recognized HPr homologues. A nitrogen-metabolic PTS phosphoryl transfer chain encoded within the rpoN and ptsP operons and a tri-domain regulatory PTS protein encoded within the dha (dihydroxyacetone catabolic) operon, probably serve regulatory roles exclusively. In addition to several additional putative regulatory proteins, there are 21 (and possibly 22) recognized Enzyme II complexes. Of the 21 Enzyme II complexes, 7 belong to the fructose (Fru) family, 7 belong to the glucose (Glc) family, and 7 belong to the other PTS permease families. All of these proteins are briefly described, and phylogenetic data for the major families are presented.

PMID:: 11361063; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Grant Support

LinkOut - more resources

Other Literature Sources

COS Scholar Universe

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Novel phosphotransferase-encoding genes revealed by analysis of the Escherichia coli genome: a chimeric gene encoding an Enzyme I homologue that possesses a putative sensory transduction domain. [Gene. 1996]
Novel phosphotransferase-encoding genes revealed by analysis of the Escherichia coli genome: a chimeric gene encoding an Enzyme I homologue that possesses a putative sensory transduction domain.
Reizer J, Reizer A, Merrick MJ, Plunkett G 3rd, Rose DJ, Saier MH Jr. Gene. 1996 Nov 28; 181(1-2):103-8.
Novel phosphotransferase system genes revealed by bacterial genome analysis: unique, putative fructose- and glucoside-specific systems. [Protein Sci. 1994]
Novel phosphotransferase system genes revealed by bacterial genome analysis: unique, putative fructose- and glucoside-specific systems.
Reizer J, Michotey V, Reizer A, Saier MH Jr. Protein Sci. 1994 Mar; 3(3):440-50.
Physiological consequences of the complete loss of phosphoryl-transfer proteins HPr and FPr of the phosphoenolpyruvate:sugar phosphotransferase system and analysis of fructose (fru) operon expression in Salmonella typhimurium. [J Bacteriol. 1990]
Physiological consequences of the complete loss of phosphoryl-transfer proteins HPr and FPr of the phosphoenolpyruvate:sugar phosphotransferase system and analysis of fructose (fru) operon expression in Salmonella typhimurium.
Feldheim DA, Chin AM, Nierva CT, Feucht BU, Cao YW, Xu YF, Sutrina SL, Saier MH Jr. J Bacteriol. 1990 Sep; 172(9):5459-69.
Review Routes for fructose utilization by Escherichia coli. [J Mol Microbiol Biotechnol. 2001]
Review Routes for fructose utilization by Escherichia coli.
Kornberg HL. J Mol Microbiol Biotechnol. 2001 Jul; 3(3):355-9.
Review Phylogeny of phosphoryl transfer proteins of the phosphoenolpyruvate-dependent sugar-transporting phosphotransferase system. [Res Microbiol. 2002]
Review Phylogeny of phosphoryl transfer proteins of the phosphoenolpyruvate-dependent sugar-transporting phosphotransferase system.
Hu KY, Saier MH Jr. Res Microbiol. 2002 Sep; 153(7):405-15.

See reviews... See all...

Cited by 29 PubMed Central articles

Functional analysis of family GH36 α-galactosidases from Ruminococcus gnavus E1: insights into the metabolism of a plant oligosaccharide by a human gut symbiont. [Appl Environ Microbiol. 2012]
Functional analysis of family GH36 α-galactosidases from Ruminococcus gnavus E1: insights into the metabolism of a plant oligosaccharide by a human gut symbiont.
Cervera-Tison M, Tailford LE, Fuell C, Bruel L, Sulzenbacher G, Henrissat B, Berrin JG, Fons M, Giardina T, Juge N. Appl Environ Microbiol. 2012 Nov; 78(21):7720-32. Epub 2012 Aug 24.
Regulatory tasks of the phosphoenolpyruvate-phosphotransferase system of Pseudomonas putida in central carbon metabolism. [MBio. 2012]
Regulatory tasks of the phosphoenolpyruvate-phosphotransferase system of Pseudomonas putida in central carbon metabolism.
Chavarría M, Kleijn RJ, Sauer U, Pflüger-Grau K, de Lorenzo V. MBio. 2012; 3(2). Epub 2012 Mar 20.
A functional genomics approach to establish the complement of carbohydrate transporters in Streptococcus pneumoniae. [PLoS One. 2012]
A functional genomics approach to establish the complement of carbohydrate transporters in Streptococcus pneumoniae.
Bidossi A, Mulas L, Decorosi F, Colomba L, Ricci S, Pozzi G, Deutscher J, Viti C, Oggioni MR. PLoS One. 2012; 7(3):e33320. Epub 2012 Mar 13.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
BioSystems
Pathways and biological systems (BioSystems) that cite the current articles. Citations are from the BioSystems source databases (KEGG and BioCyc).
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Protein Clusters
Clusters of related proteins from the Protein Clusters database that cite the current articles. Sources of references in Protein Clusters include the associated Gene and Conserved Domain records as well as NCBI added citations.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Domains
Conserved Domain Database (CDD) records that cite the current articles. Citations are from the CDD source database records (PFAM, SMART).
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

The complete phosphotransferase system in Escherichia coli.
The complete phosphotransferase system in Escherichia coli.
J Mol Microbiol Biotechnol. 2001 Jul ;3(3):329-46.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: