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Psychother Psychosom. 2001 May-Jun;70(3):145-50.

Psychiatric symptoms associated with scleroderma.

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  • 1Department of Psychiatry, Medical School, University of Thessalia, Larissa, Greece.



The prevalence of psychiatric symptoms and hostility factors in patients with scleroderma, although a matter of clinical interest, it is rather poorly studied.


Thirty female patients with scleroderma were investigated. Thirty-three healthy women were used as a comparison group. The applied psychometric instruments were the Hostility and Direction of Hostility Questionnaire (HDHQ), the Delusions Symptoms States Inventory/states of Anxiety and Depression (DSSI/sAD) and the Symptom Check List-90R (SCL-90R).


The scleroderma patients reported significantly increased depression and anxiety, somatization, interpersonal sensitivity and obsessive-compulsiveness. Paranoid ideation and psychotic symptoms scores were also increased. On hostility, they presented significantly higher scores predominantly on guilt.


Psychiatric symptomatology in the form of anxiety, depression, obsessive-compulsiveness, somatization and feelings of guilt were reported by the majority of the patients with scleroderma.

Copyright 2001 S. Karger AG, Basel

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