Abstract
The varicella-zoster virus (VZV) genome contains about 70 open reading frames (ORF). ORF 68 codes for glycoprotein gE, formerly called gpl, which is the predominant VZV glycoprotein; gE is a typical type 1 transmembrane protein with 623 amino acids. Recently, a variant virus was discovered which has a mutation in gE codon 150; this mutation converts an aspartic acid into an asparagine residue.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Amino Acid Sequence
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Antibodies, Viral / blood
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Antibodies, Viral / immunology*
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Antibody Specificity
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Antigenic Variation / genetics*
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Antigenic Variation / immunology
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Antigens, Viral / genetics*
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Antigens, Viral / immunology
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Chickenpox / blood
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Chickenpox / immunology
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Chickenpox / pathology
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Chickenpox / virology
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Child
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Cytotoxicity, Immunologic / immunology
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Epitopes, B-Lymphocyte / genetics*
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Epitopes, B-Lymphocyte / immunology
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Herpes Zoster / blood
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Herpes Zoster / immunology
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Herpes Zoster / pathology
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Herpes Zoster / virology
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Herpesvirus 3, Human / genetics*
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Herpesvirus 3, Human / immunology
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Humans
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Molecular Sequence Data
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Radioimmunoprecipitation Assay
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Tumor Cells, Cultured
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Viral Envelope Proteins / genetics*
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Viral Envelope Proteins / immunology
Substances
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Antibodies, Viral
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Antigens, Viral
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Epitopes, B-Lymphocyte
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Viral Envelope Proteins
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glycoprotein E, varicella-zoster virus