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Pharmazie. 2001 Apr;56(4):295-7.

Synthesis and biochemical evaluation of some novel N-acyl phosphono- and phosphinoalanine derivatives as potential inhibitors of the D-glutamic acid-adding enzyme.

Author information

  • 1Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia. gobecs@ffa.uni-lj.si

Abstract

A series of N-(5-phthalimidopentanoyl)-, N-[2-(2-ethoxy)acetyl]-, and N-(7-oxooctanoyl)-phosphono and phosphinoalanine derivatives has been synthesized and evaluated for inhibition of the D-glutamic acid-adding enzyme (MurD) of peptidoglycan biosynthesis.

PMID:
11338666
[PubMed - indexed for MEDLINE]
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