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EMBO J. 2001 May 1;20(9):2140-51.

The tripartite motif family identifies cell compartments.

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  • 1Telethon Institute of Genetics and Medicine (TIGEM), San Raffaele Biomedical Science Park, Milan, Italy.

Abstract

A functional genomic approach, based on systematic data gathering, was used to characterize a family of proteins containing a tripartite motif (TRIM). A total of 37 TRIM genes/proteins were studied, 21 of which were novel. The results demonstrate that TRIM proteins share a common function: by means of homo-multimerization they identify specific cell compartments.

PMID:
11331580
[PubMed - indexed for MEDLINE]
PMCID:
PMC125245
Free PMC Article

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