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J Chir (Paris). 2001 Apr;138(2):104-8.

[Gastrointestinal stromal tumors].

[Article in French]

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  • 1Service de Chirurgie Digestive, Hôpital des Gardiens de la Paix, Paris, France.


There are two main types of gastrointestinal connective tissue tumors: differentiated connective tissue tumors arising from smooth muscle tissue, schwanommas or fibroblastic tissue, and non-differentiated connective tissue tumors with no precise origin. Pathologically non-classifiable tumors comprise a group of real gastrointestinal stromal tumors. Stromal tumors are rare and generally develop in the stomach. Immunohistochemistry has been able to identify three entities: stromal tumorswith skenoid fibers, gastoinestinal autonomic nerve tumors, and intraabdominal desmoplastic small round-cell tumors. After resection, survival is almost 50% at 5 years and depends particulary on tumors size, the presence of synchronous metastases and mitosis count.

[PubMed - indexed for MEDLINE]
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