Eur Urol. 2001 Apr;39(4):484-8.

Solitary fibrous tumour of the urinary bladder with expression of bcl-2, CD34, and insulin-like growth factor type II.

Corti B, Carella R, Gabusi E, D'Errico A, Martorana G, Grigioni WF.

Source

Pathology Division of the 'Felice Addarii' Institute, Department of Oncology and Haematology, Bologna University School of Medicine, Bologna, Italy.

Abstract

We describe a solitary fibrous tumour of the urinary bladder wall removed from a 50-year-old man with a history of pelvic pain, dysuria, and urinary bleeding. Anamnesis revealed a weight increase during the preceding 3 months, but no apparent episodes of biochemical hypoglycaemia or hormonal abnormalities. The patient is alive and well 18 months after surgery. Pathological examination revealed a 6.5-cm well-circumscribed nodular mass composed of uniform spindle cells arranged in bundles and fascicles with varying amounts of collagen and a typical haemangiopericytoma-like vascular pattern. The tumour cells were positive for bcl-2, CD34, and vimentin and ultrastructurally showed mesenchymal-myofibroblastic traits. These cells produced insulin-like growth factor type II mRNA as demonstrated by non-isotopic in situ hybridization. This rare case with a solitary fibrous tumor suggests that insulin-like growth factor type II could join CD34 and bcl-2 as markers for postoperative differential diagnosis.

PMID:: 11306891; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Case Reports

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Medical

Bladder Cancer - MedlinePlus Health Information

Supplemental Content

Related citations

[Solitary fibrous tumor presenting as perivesical mass associated with hypoglycemia: a case report]. [Nihon Hinyokika Gakkai Zasshi. 2005]
[Solitary fibrous tumor presenting as perivesical mass associated with hypoglycemia: a case report].
Tsurukawa H, Komura H, Hirata T. Nihon Hinyokika Gakkai Zasshi. 2005 Nov; 96(7):709-13.
Solitary fibrous tumor of the pleura causing recurrent hypoglycemia by secretion of insulin-like growth factor II. [Pathol Int. 1998]
Solitary fibrous tumor of the pleura causing recurrent hypoglycemia by secretion of insulin-like growth factor II.
Fukasawa Y, Takada A, Tateno M, Sato H, Koizumi M, Tanaka A, Sato T. Pathol Int. 1998 Jan; 48(1):47-52.
Solitary fibrous tumour: clinicopathological, immunohistochemical, and ultrastructural analysis of 12 cases arising in soft tissues, nasal cavity and nasopharynx, urinary bladder and prostate. [Virchows Arch. 1997]
Solitary fibrous tumour: clinicopathological, immunohistochemical, and ultrastructural analysis of 12 cases arising in soft tissues, nasal cavity and nasopharynx, urinary bladder and prostate.
Mentzel T, Bainbridge TC, Katenkamp D. Virchows Arch. 1997 Jun; 430(6):445-53.
Review Large solitary fibrous tumor of the kidney: report of two cases and review of the literature. [Am J Surg Pathol. 2001]
Review Large solitary fibrous tumor of the kidney: report of two cases and review of the literature.
Wang J, Arber DA, Frankel K, Weiss LM. Am J Surg Pathol. 2001 Sep; 25(9):1194-9.
Review Solitary fibrous tumor of the urinary bladder. [Yonsei Med J. 2004]
Review Solitary fibrous tumor of the urinary bladder.
Kim SH, Cha KB, Choi YD, Cho NH. Yonsei Med J. 2004 Jun 30; 45(3):573-6.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

Recent activity

Clear Turn Off Turn On

Solitary fibrous tumour of the urinary bladder with expression of bcl-2, CD34, a...
Solitary fibrous tumour of the urinary bladder with expression of bcl-2, CD34, and insulin-like growth factor type II.
Eur Urol. 2001 Apr ;39(4):484-8.

PubMed
Origins, evolution, and phenotypic impact of new genes.
Origins, evolution, and phenotypic impact of new genes.
Genome Res. 2010 Oct ;20(10):1313-26. Epub 2010 Jul 22 .

PubMed
An organometallic protein kinase inhibitor pharmacologically activates p53 and i...
An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells.
Cancer Res. 2007 Jan 1 ;67(1):209-17.

PubMed
Cistus incanus (CYSTUS052) for treating patients with infection of the upper res...
Cistus incanus (CYSTUS052) for treating patients with infection of the upper respiratory tract. A prospective, randomised, placebo-controlled clinical study.
Antiviral Res. 2009 Dec ;84(3):267-71. Epub 2009 Oct 12 .

PubMed
The enzymatic formation of oxalacetic acid by nonpyridine nucleotide malic dehyd...
The enzymatic formation of oxalacetic acid by nonpyridine nucleotide malic dehydrogenase of Micrococcus lysodeikticus.
J Biol Chem. 1958 Aug ;233(2):299-304.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: