Genome-wide analysis of protein-DNA interactions i...[Genome Biol. 2001]

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1: Genome Biol. 2001;2(4):REVIEWS1013. Epub 2001 Apr 4. Links

Genome-wide analysis of protein-DNA interactions in living cells.

Pugh BF, Gilmour DS.

Center for Gene Regulation, Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA.

Understanding the regulation of gene expression requires an analysis of gene-specific transcription factors. This review highlights recent work that uses protein-DNA crosslinking, immunoprecipitation and DNA microarrays to determine the binding sites for specific transcription factors throughout the yeast genome.

PMID: 11305945 [PubMed - indexed for MEDLINE]

PMCID: PMC138927

Genome-wide location and function of DNA binding proteins.
Science. 2000 Dec 22; 290(5500):2306-9.

[Science. 2000]
Protein binding microarrays (PBMs) for rapid, high-throughput characterization of the sequence specificities of DNA binding proteins.
Methods Mol Biol. 2006; 338:245-60.

[Methods Mol Biol. 2006]
Genome-wide expression profiling, in vivo DNA binding analysis, and probabilistic motif prediction reveal novel Abf1 target genes during fermentation, respiration, and sporulation in yeast.
Mol Biol Cell. 2008 May; 19(5):2193-207. Epub 2008 Feb 27.

[Mol Biol Cell. 2008]
ReviewGenome-wide analysis of the context-dependence of regulatory networks.
Genome Biol. 2005; 6(2):206. Epub 2005 Jan 27.

[Genome Biol. 2005]
ReviewDNA protein interactions at the rRNA of Saccharomyces cerevisiae.
Ital J Biochem. 2007 Jun; 56(2):81-90.

[Ital J Biochem. 2007]
» See reviews... | » See all...

Cited by 1 PubMed Central article

Chipper: discovering transcription-factor targets from chromatin immunoprecipitation microarrays using variance stabilization.
Gibbons FD, Proft M, Struhl K, Roth FP. Genome Biol. 2005; 6(11):R96. Epub 2005 Nov 1.

[Genome Biol. 2005]

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