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1: Genome Biol. 2001;2(4):REVIEWS0003. Epub 2001 Apr 5.Click here to read Click here to read Links

A tale of histone modifications.

Grant PA.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Jefferson Park Avenue, Charlottesville, VA 22908, USA. pag9n@virginia.edu

The modification of chromatin structure is important for a number of nuclear functions, exemplified by the regulation of transcription. This review discusses recent studies of covalent histone modifications and the enzymatic machines that generate them.

PMID: 11305943 [PubMed - indexed for MEDLINE]

PMCID: PMC138925

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