Approaches to memory loss in neuropsychiatric disorders

Semin Clin Neuropsychiatry. 2000 Oct;5(4):259-65. doi: 10.1053/scnp.2000.16528.

Abstract

Many neuropsychiatric disorders affect memory. Brain regions important in the neuroanatomic substrate of memory include the hippocampus, and sections of the frontal, temporal, and parietal cortices and the thalamus. Acetylcholine and many other neurotransmitters and neuromodulators including dopamine, glutamate, GABA, the catecholamines, and estrogen modulate cognitive function. Treatment approaches to memory loss typically use Alzheimer's dementia as the template, and are discussed in this report.

Publication types

  • Review

MeSH terms

  • Aging / psychology*
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Antioxidants / therapeutic use
  • Cholinesterase Inhibitors / therapeutic use
  • Dementia / complications*
  • Donepezil
  • Estrogen Replacement Therapy
  • Humans
  • Indans / therapeutic use
  • Memory Disorders / drug therapy*
  • Memory Disorders / etiology
  • Memory Disorders / therapy
  • Nootropic Agents / therapeutic use*
  • Piperidines / therapeutic use
  • Premenopause / psychology*
  • Randomized Controlled Trials as Topic
  • Tacrine / therapeutic use

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Antioxidants
  • Cholinesterase Inhibitors
  • Indans
  • Nootropic Agents
  • Piperidines
  • Tacrine
  • Donepezil