Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Bull World Health Organ. 2001;79(3):194-200. Epub 2003 Jul 7.

Comparison of two azithromycin distribution strategies for controlling trachoma in Nepal.

Author information

  • 1Francis I. Proctor Foundation for Research in Ophthalmology, University of California, San Francisco, CA, USA.

Abstract

OBJECTIVE:

The study compares the effectiveness of two strategies for distributing azithromycin in an area with mild-to-moderate active trachoma in Nepal.

METHODS:

The two strategies investigated were the use of azithromycin for 1) mass treatment of all children, or 2) targeted treatment of only those children who were found to be clinically active, as well as all members of their household.

FINDINGS:

Mass treatment of children was slightly more effective in terms of decreasing the prevalence of clinically active trachoma (estimated by clinical examination) and of chlamydial infection (estimated by DNA amplification tests), although neither result was statistically significant.

CONCLUSION:

Both strategies appeared to be effective in reducing the prevalence of clinically active trachoma and infection six months after the treatment. Antibiotic treatment reduced the prevalence of chlamydial infection more than it did the level of clinically active trachoma.

PMID:
11285662
[PubMed - indexed for MEDLINE]
PMCID:
PMC2566365
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Scientific Electronic Library Online Icon for PubMed Central
    Loading ...
    Write to the Help Desk