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Teratology. 2001 Mar;63(3):161-3.

Recurrent cleft lip and palate in siblings of a patient with malabsorption syndrome, probably caused by hypovitaminosis a associated with folic acid and vitamin B(2) deficiencies.

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  • 1Department of Obstetrics, Centre Hospitalier Universitaire de Québec (CHUQ), Université Laval, Québec, Québec, Canada. gilles.faron@chu-brugman.bc


We present a woman with metabolic disorders secondary to malabsorption and renal disease who gave birth to a stillborn male fetus with left unilateral cleft lip and palate and a live born infant with left unilateral cleft lip and palate. We discuss potential cofactors that could be implicated in the abnormal embryonic process.

Copyright 2001 Wiley-Liss, Inc.

[PubMed - indexed for MEDLINE]
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