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Laboratoire de Neurosciences Cognitives et Imagerie Cérébrale, Hôpital de la Salpétrière, Paris 47 Boulevard de l'Hôpital, 75651 Paris Cedex 13, France. fv@ccr.jussieu.fr
The emergence of a unified cognitive moment relies on the coordination of scattered mosaics of functionally specialized brain regions. Here we review the mechanisms of large-scale integration that counterbalance the distributed anatomical and functional organization of brain activity to enable the emergence of coherent behaviour and cognition. Although the mechanisms involved in large-scale integration are still largely unknown, we argue that the most plausible candidate is the formation of dynamic links mediated by synchrony over multiple frequency bands.
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