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    Bioorg Med Chem Lett. 2001 Mar 12;11(5):635-9.

    3-Anilino-4-arylmaleimides: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3).

    Source

    SmithKline Beecham Pharmaceuticals, New Frontiers Science Park, Harlow, Essex, UK. dave_g_smith@sbphrd.com

    Abstract

    Potent 3-anilino-4-arylmaleimide glycogen synthase kinase-3 (GSK-3) inhibitors have been prepared using automated array methodology. A number of these are highly selective, having little inhibitory potency against more than 20 other protein kinases.

    PMID:
    11266159
    [PubMed - indexed for MEDLINE]

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