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Metabolism of fluorine-containing drugs.

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  • 1Department of Pharmacology and Therapeutics, New Medical Building, University of Liverpool, Liverpool, United Kingdom. bkpark@liverpool.ac.uk

Abstract

This article reviews current knowledge of the metabolism of drugs that contain fluorine. The strategic value of fluorine substitution in drug design is discussed in terms of chemical structure and basic concepts in drug metabolism and drug toxicity.

PMID:
11264465
[PubMed - indexed for MEDLINE]
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