11257232,11359776,11447297,11927604,15200957,15608231,15650747,16189514,9230442,9384571,9525868,11230124,16501604,17145710,10469173,11423904,11514563,12438416,11802788,11098060,11261798,11098060,16713569,9933635,16179924,10556977,16189514,11162250,12 - Search Results

Year	Number of Results
1995	1
1996	2
1997	9
1998	13
1999	9
2000	15
2001	27
2002	14
2003	1
2004	5
2005	7
2006	6
2007	3
2008	1
2024	0

1

Structural basis for the inhibition of caspase-3 by XIAP.

Riedl SJ, Renatus M, Schwarzenbacher R, Zhou Q, Sun C, Fesik SW, Liddington RC, Salvesen GS. Riedl SJ, et al. Cell. 2001 Mar 9;104(5):791-800. doi: 10.1016/s0092-8674(01)00274-4. Cell. 2001. PMID: 11257232 Free article.

2

X-linked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and -7 in distinct modes.

Suzuki Y, Nakabayashi Y, Nakata K, Reed JC, Takahashi R. Suzuki Y, et al. J Biol Chem. 2001 Jul 20;276(29):27058-63. doi: 10.1074/jbc.M102415200. Epub 2001 May 18. J Biol Chem. 2001. PMID: 11359776 Free article.

3

Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death.

Suzuki Y, Nakabayashi Y, Takahashi R. Suzuki Y, et al. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8662-7. doi: 10.1073/pnas.161506698. Epub 2001 Jul 10. Proc Natl Acad Sci U S A. 2001. PMID: 11447297 Free PMC article.

4

The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites.

Silke J, Hawkins CJ, Ekert PG, Chew J, Day CL, Pakusch M, Verhagen AM, Vaux DL. Silke J, et al. J Cell Biol. 2002 Apr 1;157(1):115-24. doi: 10.1083/jcb.200108085. Epub 2002 Apr 1. J Cell Biol. 2002. PMID: 11927604 Free PMC article.

5

Dual role of BRUCE as an antiapoptotic IAP and a chimeric E2/E3 ubiquitin ligase.

Bartke T, Pohl C, Pyrowolakis G, Jentsch S. Bartke T, et al. Mol Cell. 2004 Jun 18;14(6):801-11. doi: 10.1016/j.molcel.2004.05.018. Mol Cell. 2004. PMID: 15200957 Free article.

6

XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs.

Scott FL, Denault JB, Riedl SJ, Shin H, Renatus M, Salvesen GS. Scott FL, et al. EMBO J. 2005 Feb 9;24(3):645-55. doi: 10.1038/sj.emboj.7600544. Epub 2005 Jan 13. EMBO J. 2005. PMID: 15650747 Free PMC article.

7

X-linked IAP is a direct inhibitor of cell-death proteases.

Deveraux QL, Takahashi R, Salvesen GS, Reed JC. Deveraux QL, et al. Nature. 1997 Jul 17;388(6639):300-4. doi: 10.1038/40901. Nature. 1997. PMID: 9230442

8

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases.

Roy N, Deveraux QL, Takahashi R, Salvesen GS, Reed JC. Roy N, et al. EMBO J. 1997 Dec 1;16(23):6914-25. doi: 10.1093/emboj/16.23.6914. EMBO J. 1997. PMID: 9384571 Free PMC article.

9

A single BIR domain of XIAP sufficient for inhibiting caspases.

Takahashi R, Deveraux Q, Tamm I, Welsh K, Assa-Munt N, Salvesen GS, Reed JC. Takahashi R, et al. J Biol Chem. 1998 Apr 3;273(14):7787-90. doi: 10.1074/jbc.273.14.7787. J Biol Chem. 1998. PMID: 9525868 Free article.

10

Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes.

Bratton SB, Walker G, Srinivasula SM, Sun XM, Butterworth M, Alnemri ES, Cohen GM. Bratton SB, et al. EMBO J. 2001 Mar 1;20(5):998-1009. doi: 10.1093/emboj/20.5.998. EMBO J. 2001. PMID: 11230124 Free PMC article.

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