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Nat Rev Genet. 2001 Mar;2(3):228-31.

Ethical and legal implications of pharmacogenomics.

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  • 1Institute for Bioethics, Health Policy and Law, University of Louisville School of Medicine, 101 West Chestnut, Louisville, Kentucky 40202, USA.


Pharmacogenomics is the application of genomics technology to the discovery and development of drugs. A greater understanding of the way in which individuals with a particular genotype respond to a drug allows manufacturers to identify population subgroups that will benefit most from a particular drug. The increasing emphasis on pharmacogenomics is likely to raise ethical and legal questions regarding, among other things, the design of research studies, the construction of clinical trials and the pricing of drugs.

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