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Nat Rev Mol Cell Biol. 2000 Dec;1(3):187-98.

Three ways to make a vesicle.

Author information

  • Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts 02115, USA. kirchhausen@crystal.harvard.edu

Erratum in

  • Nat Rev Mol Cell Biol 2001 Mar;2(3):216.

Abstract

Cargo molecules have to be included in carrier vesicles of different forms and sizes to be transported between organelles. During this process, a limited set of proteins, including the coat proteins COPI, COPII and clathrin, carries out a programmed set of sequential interactions that lead to the budding of vesicles. A general model to explain the formation of coated vesicles is starting to emerge but the picture is more complex than we had imagined.

PMID:
11252894
[PubMed - indexed for MEDLINE]
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