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    Nat Rev Mol Cell Biol. 2000 Dec;1(3):187-98.

    Three ways to make a vesicle.

    Kirchhausen T.

    Source

    Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts 02115, USA. kirchhausen@crystal.harvard.edu

    Erratum in

    • Nat Rev Mol Cell Biol 2001 Mar;2(3):216.

    Abstract

    Cargo molecules have to be included in carrier vesicles of different forms and sizes to be transported between organelles. During this process, a limited set of proteins, including the coat proteins COPI, COPII and clathrin, carries out a programmed set of sequential interactions that lead to the budding of vesicles. A general model to explain the formation of coated vesicles is starting to emerge but the picture is more complex than we had imagined.

    PMID:
    11252894
    [PubMed - indexed for MEDLINE]

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