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Breast Cancer Res. 2000;2(5):360-6. Epub 2000 Jul 13.

Estrogen receptor transcription and transactivation: Basic aspects of estrogen action.

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  • 1KaroBio AB, Huddinge, Sweden.

Abstract

Estrogen signaling has turned out to be much more complex and exciting than previously thought; the paradigm shift in our understanding of estrogen action came in 1996, when the presence of a new estrogen receptor (ER), ERbeta, was reported. An intricate interplay between the classical ERalpha and the novel ERbeta is of paramount importance for the final biological effect of estrogen in different target cells.

PMID:
11250729
[PubMed - indexed for MEDLINE]
PMCID:
PMC138658
Free PMC Article
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