Trends Biochem Sci. 2001 Mar;26(3):167-74.

HMG1 and 2, and related 'architectural' DNA-binding proteins.

Source

Cambridge Centre for Molecular Recognition, University of Cambridge, 80 Tennis Court Road, Cambridge, UK CB2 1GA. jot1@bioc.cam.ac.uk

Erratum in

Trends Biochem Sci 2001 Apr;26(4):219.

Abstract

The HMG-box proteins, one of the three classes of high mobility group (HMG) chromosomal proteins, bend DNA and bind preferentially to distorted DNA structures. The proteins appear to act primarily as architectural facilitators in the assembly of nucleoprotein complexes; for example, in effecting recombination and in the initiation of transcription. HMG-box proteins might be targeted to particular DNA sites in chromatin by either protein-protein interactions or recognition of specific DNA structures.

PMID:: 11246022; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Review

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Supplemental Content

Save items

Related citations in PubMed

Formation of large nucleoprotein complexes upon binding of the high-mobility-group (HMG) box B-domain of HMG1 protein to supercoiled DNA. [Eur J Biochem. 1998]
Formation of large nucleoprotein complexes upon binding of the high-mobility-group (HMG) box B-domain of HMG1 protein to supercoiled DNA.
Stros M, Reich J. Eur J Biochem. 1998 Jan 15; 251(1-2):427-34.
The effect of the acidic tail on the DNA-binding properties of the HMG1,2 class of proteins: insights from tail switching and tail removal. [J Mol Biol. 2000]
The effect of the acidic tail on the DNA-binding properties of the HMG1,2 class of proteins: insights from tail switching and tail removal.
Lee KB, Thomas JO. J Mol Biol. 2000 Nov 24; 304(2):135-49.
Review HMG1 and 2: architectural DNA-binding proteins. [Biochem Soc Trans. 2001]
Review HMG1 and 2: architectural DNA-binding proteins.
Thomas JO. Biochem Soc Trans. 2001 Aug; 29(Pt 4):395-401.
Solution structure of the HMG protein NHP6A and its interaction with DNA reveals the structural determinants for non-sequence-specific binding. [EMBO J. 1999]
Solution structure of the HMG protein NHP6A and its interaction with DNA reveals the structural determinants for non-sequence-specific binding.
Allain FH, Yen YM, Masse JE, Schultze P, Dieckmann T, Johnson RC, Feigon J. EMBO J. 1999 May 4; 18(9):2563-79.
Review Nonsequence-specific DNA recognition: a structural perspective. [Structure. 2000]
Review Nonsequence-specific DNA recognition: a structural perspective.
Murphy FV 4th, Churchill ME. Structure. 2000 Apr 15; 8(4):R83-9.

See reviews... See all...

Cited by over 100 PubMed Central articles

RAG and HMGB1 create a large bend in the 23RSS in the V(D)J recombination synaptic complexes. [Nucleic Acids Res. 2013]
RAG and HMGB1 create a large bend in the 23RSS in the V(D)J recombination synaptic complexes.
Ciubotaru M, Trexler AJ, Spiridon LN, Surleac MD, Rhoades E, Petrescu AJ, Schatz DG. Nucleic Acids Res. 2013 Feb 1; 41(4):2437-54. Epub 2013 Jan 4.
Structural insight into the ligand-receptor interaction between glycyrrhetinic acid (GA) and the high-mobility group protein B1 (HMGB1)-DNA complex. [Bioinformation. 2012]
Structural insight into the ligand-receptor interaction between glycyrrhetinic acid (GA) and the high-mobility group protein B1 (HMGB1)-DNA complex.
Yamaguchi H, Kidachi Y, Kamiie K, Noshita T, Umetsu H. Bioinformation. 2012; 8(23):1147-53. Epub 2012 Nov 23.
Crenarchaeal chromatin proteins Cren7 and Sul7 compact DNA by inducing rigid bends. [Nucleic Acids Res. 2013]
Crenarchaeal chromatin proteins Cren7 and Sul7 compact DNA by inducing rigid bends.
Driessen RP, Meng H, Suresh G, Shahapure R, Lanzani G, Priyakumar UD, White MF, Schiessel H, van Noort J, Dame RT. Nucleic Acids Res. 2013 Jan 7; 41(1):196-205. Epub 2012 Nov 15.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Gene
Gene records that cite the current articles. Citations in Gene are added manually by NCBI or imported from outside public resources.
HomoloGene
HomoloGene clusters of homologous genes and sequences that cite the current articles. These are references on the Gene and sequence records in the HomoloGene entry.
Nucleotide (RefSeq)
NCBI nucleotide Reference Sequences (RefSeqs) that are cited in the current articles, included in the corresponding Gene Reference into Function, or that include the PubMed articles as references.
Nucleotide (Weighted)
Nucleotide records associated with the current articles through the Gene database. These are the related sequences on the Gene record that are added manually by NCBI.
Protein (RefSeq)
NCBI protein Reference Sequences (RefSeqs) that are cited in the current articles, included in the corresponding Gene Reference into Function, or that include the PubMed articles as references.
Protein (Weighted)
Protein records associated with the current articles through related Gene database records. These are the related sequences on the Gene record that are added manually by NCBI.
Protein Clusters
Clusters of related proteins from the Protein Clusters database that cite the current articles. Sources of references in Protein Clusters include the associated Gene and Conserved Domain records as well as NCBI added citations.
Taxonomy via GenBank
Taxonomy records associated with the current articles through taxonomic information on related molecular database records (Nucleotide, Protein, Gene, SNP, Structure).
UniGene
UniGene clusters of expressed sequences that are associated with the current articles through references on the clustered sequence records and related Gene records.
Domains
Conserved Domain Database (CDD) records that cite the current articles. Citations are from the CDD source database records (PFAM, SMART).
GEO Profiles
Gene Expression Omnibus (GEO) Profiles of molecular abundance data. The current articles are references on the Gene record associated with the GEO profile.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

HMG1 and 2, and related 'architectural' DNA-binding proteins.
HMG1 and 2, and related 'architectural' DNA-binding proteins.
Trends Biochem Sci. 2001 Mar ;26(3):167-74.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: