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1: Physiol Behav. 2001 Jan;72(1-2):205-16.Click here to read Links

Adaptation to capsaicin burn: effects of concentration and individual differences.

McBurney DH, Balaban CD, Popp JR, Rosenkranz JE.

Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA.

Human subjects rated the time course of the burn produced by three concentrations of capsaicin applied to the tongue via filter papers. Data were fit to a dynamic model composed of a level detector, a change detector, and a double integrator. These three processes responded differently to concentration. 6-n-Propyl-2-thiouracil (PROP) taster status correlated positively with the integrator process. Although a minority of subjects showed evidence of the integrator process, any subject with an integrator process at a given concentration also showed it at any higher concentration.

PMID: 11239999 [PubMed - indexed for MEDLINE]

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