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Nat Med. 2001 Mar;7(3):271-4.

Immune privilege or inflammation? Insights into the Fas ligand enigma.

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  • 1Department of Medicine, University Hospital, National University of Ireland, Cork, Ireland. j.oconnell@ucc.ie

Abstract

Fas ligand (FasL) has become an enigmatic molecule: some evidence indicates that it contributes to immune privilege in tissues and tumors, whereas other data demonstrates that FasL can elicit inflammation. New findings may begin to reconcile the paradoxical effects of FasL.

PMID:
11231613
[PubMed - indexed for MEDLINE]
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