Tumor necrosis factor promoter polymorphism (TNF2) seems to protect against development of severe forms of leprosy in a pilot study in Brazilian patients

Int J Lepr Other Mycobact Dis. 2000 Sep;68(3):325-7.
No abstract available

Publication types

  • Comparative Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Brazil
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / isolation & purification
  • Deoxyribonucleases, Type II Site-Specific / chemistry
  • Humans
  • Leprosy, Tuberculoid / genetics
  • Leprosy, Tuberculoid / immunology*
  • Mycobacterium leprae / genetics
  • Mycobacterium leprae / immunology*
  • Pilot Projects
  • Polymerase Chain Reaction
  • Polymorphism, Genetic / genetics
  • Polymorphism, Genetic / immunology
  • Tumor Necrosis Factor-alpha / genetics
  • Tumor Necrosis Factor-alpha / immunology*

Substances

  • DNA, Bacterial
  • Tumor Necrosis Factor-alpha
  • endodeoxyribonuclease NcoI
  • Deoxyribonucleases, Type II Site-Specific