[Malignant neuroleptic syndrome or serotonergic syndrome]

H:S Bispebjerg Hospital, psykiatrisk afdeling E.

The malignant neuroleptica syndrome (MNS) and the serotonin syndrome (SS) can be impossible to differentiate. This case history describes clinical symptoms compatible with either MNS or SS in a 59-year-old schizophrenic male patient, who had been heavily medicated with antipsychotics for several years in close relation to initiation of new treatment with a SSRI compound. The case shows that it is important to have both syndromes in mind when chronically ill patients are treated with several medicaments.

PMID: 11219110 [PubMed - indexed for MEDLINE]