Targeting tumor vasculature using VEGF-toxin conjugates

Methods Mol Biol. 2001:166:219-34. doi: 10.1385/1-59259-114-0:219.
No abstract available

Publication types

  • Review

MeSH terms

  • Angiogenesis Inhibitors / chemistry
  • Angiogenesis Inhibitors / isolation & purification
  • Angiogenesis Inhibitors / pharmacology
  • Angiogenesis Inhibitors / therapeutic use*
  • Angiogenic Proteins*
  • Animals
  • Cell Line / drug effects
  • Chick Embryo
  • Collagen
  • Cross-Linking Reagents
  • Dimerization
  • Diphtheria Toxin / chemistry
  • Diphtheria Toxin / isolation & purification
  • Diphtheria Toxin / pharmacology
  • Diphtheria Toxin / therapeutic use*
  • Drug Combinations
  • Drug Design
  • Endothelial Growth Factors / chemistry
  • Endothelial Growth Factors / genetics
  • Endothelial Growth Factors / isolation & purification
  • Endothelial Growth Factors / pharmacology
  • Endothelial Growth Factors / physiology
  • Endothelial Growth Factors / therapeutic use*
  • Endothelium, Vascular / cytology
  • Exons / genetics
  • Female
  • Humans
  • Laminin
  • Lymphokines / chemistry
  • Lymphokines / genetics
  • Lymphokines / isolation & purification
  • Lymphokines / pharmacology
  • Lymphokines / physiology
  • Lymphokines / therapeutic use*
  • Mice
  • Mice, Nude
  • Models, Molecular
  • Protein Folding
  • Protein Isoforms / chemistry
  • Protein Isoforms / genetics
  • Protein Isoforms / physiology
  • Proteoglycans
  • Proto-Oncogene Proteins / metabolism
  • Receptor Protein-Tyrosine Kinases / metabolism
  • Receptors, Growth Factor / metabolism
  • Receptors, Vascular Endothelial Growth Factor
  • Recombinant Fusion Proteins / chemistry
  • Recombinant Fusion Proteins / isolation & purification
  • Recombinant Fusion Proteins / pharmacology
  • Recombinant Fusion Proteins / therapeutic use
  • Tumor Cells, Cultured
  • Umbilical Veins / cytology
  • Vascular Endothelial Growth Factor A
  • Vascular Endothelial Growth Factor Receptor-1
  • Vascular Endothelial Growth Factors
  • Xenograft Model Antitumor Assays

Substances

  • Angiogenesis Inhibitors
  • Angiogenic Proteins
  • Cross-Linking Reagents
  • Diphtheria Toxin
  • Drug Combinations
  • Endothelial Growth Factors
  • Laminin
  • Lymphokines
  • Protein Isoforms
  • Proteoglycans
  • Proto-Oncogene Proteins
  • Receptors, Growth Factor
  • Recombinant Fusion Proteins
  • VEGF121-diphtheria toxin conjugate
  • VEGFA protein, human
  • Vascular Endothelial Growth Factor A
  • Vascular Endothelial Growth Factors
  • matrigel
  • Collagen
  • Receptor Protein-Tyrosine Kinases
  • Receptors, Vascular Endothelial Growth Factor
  • Vascular Endothelial Growth Factor Receptor-1