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Aging (Milano). 2000 Dec;12(6):407-16.

Gender differences in morbidity and mortality related to depression: a review of the literature.

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  • 1Department of Public Health Sciences, Wake Forest University, North Carolina 27157-1063, USA. msevick@wfubmc.edu


In this review of the existing evidence regarding a gender-specific association of depression with major health outcomes in older adults, we were unable to confirm that relative risk of morbidity and/or mortality due to depression varies with respect to gender. Future researchers may wish to concentrate their efforts in the identification of possible biophysiologic mechanisms underlying the association between depression and a variety of health outcomes.

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