Format

Send to:

Choose Destination
See comment in PubMed Commons below
Neurol Sci. 2000;21(4 Suppl 2):S843-7.

Is multiple sclerosis severity a genetically influenced trait?

Author information

  • 1Department of Neuroscience, University of Cagliari, Multiple Sclerosis Center, Ospedale Binaghi, Italy.

Abstract

Multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system of unknown pathogenesis, is a complex disease with a multifactorial etiology determined by both genetic and environmental factors. The pathological entity MS has a wide phenotype, and also the severity of the disease is widely variable. Clinical heterogeneity of the disease might arise from different genotype-phenotype interactions. Results of recent studies and theories about the modifying role of different genes in the course and the severity of MS are here discussed.

PMID:
11205360
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Springer
    Loading ...
    Write to the Help Desk