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Lancet. 2001 Jan 6;357(9249):42-3.

Multidrug-resistance protein 1 in focal cortical dysplasia.

Abstract

Drug resistance in epilepsy is poorly understood. We used routine immunohistochemistry to assess overexpression of a multidrug-resistance protein in dysplastic neurons, glia, and around vessels in surgically resected epileptogenic human brain tissue. We showed non-tumoral overexpression of this multidrug-resistance protein, which might contribute to drug resistance in epilepsy caused by focal cortical dysplasia.

PMID:
11197364
[PubMed - indexed for MEDLINE]
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