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Genome Biol. 2001;2(1):COMMENT2001. Epub 2000 Dec 20.

Polymorphism in regulatory gene sequences.

Author information

  • Department of Immunology, Windeyer Institute of Medical Science, University College London Medical School, Cleveland Street, London W1P 6DB, UK. n.mitchison@ucl.ac.uk

Abstract

The extensive polymorphism revealed in non-coding gene-regulatory sequences, particularly in the immune system, suggests that this type of genetic variation is functionally and evolutionarily far more important than has been suspected, and provides a lead to new therapeutic strategies.

PMID:
11178274
[PubMed - indexed for MEDLINE]
PMCID:
PMC150430
Free PMC Article

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