Polymorphism in regulatory gene sequences. [Genome Biol. 2001]

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1: Genome Biol. 2001;2(1):COMMENT2001. Epub 2000 Dec 20. Links

Polymorphism in regulatory gene sequences.

Mitchison NA.

Department of Immunology, Windeyer Institute of Medical Science, University College London Medical School, Cleveland Street, London W1P 6DB, UK. n.mitchison@ucl.ac.uk

The extensive polymorphism revealed in non-coding gene-regulatory sequences, particularly in the immune system, suggests that this type of genetic variation is functionally and evolutionarily far more important than has been suspected, and provides a lead to new therapeutic strategies.

PMID: 11178274 [PubMed - indexed for MEDLINE]

PMCID: PMC150430

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Cited by 1 PubMed Central article

Polymorphisms in the trace amine receptor 4 (TRAR4) gene on chromosome 6q23.2 are associated with susceptibility to schizophrenia.
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[Am J Hum Genet. 2004]

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