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Genome Biol. 2000;1(2):REVIEWS1013. Epub 2000 Aug 4.

A molecular portrait of the response to unfolded proteins.

Author information

  • 1Department of Biology, University of Nevada, Reno, NV 89557, USA. mccrake@unr.edu

Abstract

Using DNA microarrays, 381 genes have been found to be induced in response to unfolded proteins. The identity of the previously characterized 208 of these, and further experiments, have revealed new details on the scope of the unfolded protein response and its connection to the degradation of proteins at the endoplasmic reticulum.

PMID:
11178235
[PubMed - indexed for MEDLINE]
PMCID:
PMC138850
Free PMC Article

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