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Nat Genet. 2001 Feb;27(2):134-5.

Prostate cancer: simplicity to complexity.

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  • 1Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109-1024, USA.


Prostate cancer is a complex disease to which a multitude of genetic and environmental factors contribute. Two new studies offer insights as to how the disease may arise and progress. The first describes mapping and cloning of a new candidate gene, ELAC2, whereas the second demonstrates how cooperation between Cdkn1b and Pten contribute to suppression of prostate tumors.

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