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Diagn Microbiol Infect Dis. 2001 Jan;39(1):61-4.

Analysis on distribution of insertion sequence IS431 in clinical isolates of staphylococci.

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  • 1Department of Hygiene, Sapporo Medical University School of Medicine, S-1, W-17, Chuo-ku, 060-8556, Sapporo,


Distribution of insertion sequence IS431 in clinical isolates of Staphylococcus aureus, Staphylococcus epidermidis, and Staphylococcus haemolyticus was investigated. Except for methicillin susceptible-S. aureus (MSSA), IS431 was detected in all isolates of the three staphylococcal species. In MSSA, only 20% of isolates with distinct coagulase types and genetic types possessed IS431. In a few MSSA isolates, an IS431 variant with internal deletion was found.

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