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    Trends Genet. 2001 Feb;17(2):56-60.

    Identification and analysis of eukaryotic promoters: recent computational approaches.

    Ohler U, Niemann H.

    Lehrstuhl für Mustererkennung (Informatik V), Universität Erlangen-Nürnberg, Martensstr. 3, D-91058, Erlangen, Germany. Uwe.Ohler@informatik.uni-erlangen.de

    The DNA sequence of several higher eukaryotes is now complete, and we know the expression patterns of thousands of genes under a variety of conditions. This gives us the opportunity to identify and analyze the parts of a genome believed to be responsible for most transcription control--the promoters. This article gives a short overview of the state-of-the-art techniques for computational promoter localization and analysis, and comments on the most recent advances in the field.

    PMID: 11173099 [PubMed - indexed for MEDLINE]

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