Send to

Choose Destination
See comment in PubMed Commons below
Biochem J. 2001 Feb 1;353(Pt 3):441-4.

An uncoupling protein homologue putatively involved in facultative muscle thermogenesis in birds.

Author information

  • 1Centre de Recherches sur l'Endocrinologie MolĂ©culaire et le DĂ©veloppement, CNRS, 9 rue Jules Hetzel, F-92190 Meudon, France.


The cDNA of an uncoupling protein (UCP) homologue was obtained by screening a chicken skeletal-muscle library. The predicted 307-amino-acid sequence of avian UCP (avUCP) is 55, 70, 70 and 46% identical with mammalian UCP1, UCP2 and UCP3 and plant UCP respectively. avUCP mRNA expression is restricted to skeletal muscle and its abundance was increased 1.3-fold in a chicken line showing diet-induced thermogenesis, and 3.6- and 2.6-fold in cold-acclimated and glucagon-treated ducklings developing muscle non-shivering thermogenesis respectively. The present data support the implication of avUCP in avian energy expenditure.

[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk