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Trends Biochem Sci. 2001 Feb;26(2):85-7.

PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases.

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  • 1Program in Bioinformatics and Biological Complexity, The Burnham Institute, 10901 N. Torrey Pines Road, La Jolla, CA 92037, USA.


A new protein domain was found in several proteins involved in apoptosis, inflammation, cancer and immune responses. Its location within these proteins and predicted fold suggests that it functions as a protein-protein interaction domain, possibly uniting different signaling pathways.

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