Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Br J Psychiatry. 2001 Feb;178:107-15.

Therapeutic aspects of cannabis and cannabinoids.

Author information

  • Warneford Hospital, Oxford OX3 7JX, UK.

Abstract

BACKGROUND:

Review commissioned in 1996 by the Department of Health (DOH).

AIMS:

Assess therapeutic profile of cannabis and cannabinoids.

METHOD:

Medline search, references supplied by DOH and others, and personal communications.

RESULTS AND CONCLUSIONS:

Cannabis and some cannabinoids are effective anti-emetics and analgesics and reduce intra-ocular pressure. There is evidence of symptom relief and improved well-being in selected neurological conditions, AIDS and certain cancers. Cannabinoids may reduce anxiety and improve sleep. Anticonvulsant activity requires clarification. Other properties identified by basic research await evaluation. Standard treatments for many relevant disorders are unsatisfactory. Cannabis is safe in overdose but often produces unwanted effects, typically sedation, intoxication, clumsiness, dizziness, dry mouth, lowered blood pressure or increased heart rate. The discovery of specific receptors and natural ligands may lead to drug developments. Research is needed to optimise dose and route of administration, quantify therapeutic and adverse effects, and examine interactions.

Comment in

PMID:
11157423
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for HighWire
    Loading ...
    Write to the Help Desk