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    Clin Chem Lab Med. 2000 Nov;38(11):1111-3.

    Evaluation of a fully automated assay to measure C-telopeptide of type I collagen in serum.

    Pagani F, Bonetti G, Stefini F, Panteghini M.

    Source

    Laboratorio Analisi Chimico Cliniche 1, Azienda Ospedaliera Spedali Civili, Brescia, Italy.

    Abstract

    The measurement of the degradation product of the C-telopeptide of type I collagen in serum (s-betaCTX) has been evaluated in the form of an automated chemiluminometric assay. The between-day coefficients of variation ranged between 2.6 and 6.0% over the concentration range 0.12 to 3.25 microg/l. The s-betaCTX value correlated well with alternative serum C-telopeptide (r = 0.983) and urine deoxypyridinoline (r = 0.729) measurements. A significant inverse correlation was found between the s-betaCTX measurement and creatinine clearance in patients with renal disease.

    PMID:
    11156338
    [PubMed - indexed for MEDLINE]

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