Curr Psychiatry Rep. 2000 Feb;2(1):67-71.

Intermittent explosive disorder.

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Clinical Neuroscience and Psychopharmacology Research Unit, The Pritzker School of Medicine, The University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA. ecoccaro@yoda.bsd.uchicago.edu

Abstract

Intermittent explosive disorder (IED) may best be thought of as a categoric expression of recurrent, problematic impulsive aggressive behavior. Although diagnostic criteria issues have made systematic research in IED difficult, recent work with new research criteria may allow for important empiric work to take place. Given that previous research in the area of impulsive aggression has been highly informative concerning the genetics, biology, and pharmacologic treatment of this behavior, application and extension of this work to IED is crucial. This paper reviews several important aspects of IED including its history in the Diagnostic and Statistical Manual of Mental Disorders, the formation of new research criteria, and the phenomenologic, epidemiologic, genetic, biologic, and treatment correlates of this disorder.

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Intermittent explosive disorder-revised: development, reliability, and validity of research criteria. [Compr Psychiatry. 1998]
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Coccaro EF, Kavoussi RJ, Berman ME, Lish JD. Compr Psychiatry. 1998 Nov-Dec; 39(6):368-76.
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Review [Intermittent explosive disorder: current status]. [Encephale. 2007]
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Cited by 2 PubMed Central articles

Epidemiological aspects of intermittent explosive disorder in Japan; prevalence and psychosocial comorbidity: findings from the World Mental Health Japan Survey 2002-2006. [Psychiatry Res. 2011]
Epidemiological aspects of intermittent explosive disorder in Japan; prevalence and psychosocial comorbidity: findings from the World Mental Health Japan Survey 2002-2006.
Yoshimasu K, Kawakami N, WMH-J 2002-2006 Survey Group. Psychiatry Res. 2011 Apr 30; 186(2-3):384-9. Epub 2010 Aug 14.
The prevalence and correlates of DSM-IV intermittent explosive disorder in the National Comorbidity Survey Replication. [Arch Gen Psychiatry. 2006]
The prevalence and correlates of DSM-IV intermittent explosive disorder in the National Comorbidity Survey Replication.
Kessler RC, Coccaro EF, Fava M, Jaeger S, Jin R, Walters E. Arch Gen Psychiatry. 2006 Jun; 63(6):669-78.

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