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Trends Plant Sci. 2000 Dec;5(12):543-7.

The plant kinetochore.

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  • 1Dept of Botany, University of Georgia, Athens, GA 30602, USA.

Abstract

Kinetochores are large protein complexes that bind to centromeres. By interacting with microtubules and their associated motor proteins, kinetochores both generate and regulate chromosome movement. Kinetochores also function in the spindle checkpoint; a surveillance mechanism that ensures that metaphase is complete before anaphase begins. Although the ultrastructure of plant kinetochores has been known for many years, only recently have specific kinetochore proteins been identified. The recent data indicate that plant kinetochores contain homologs of many of the proteins implicated in animal and fungal kinetochore function, and that the plant kinetochore is a redundant structure with distinct biochemical subdomains.

PMID:
11120477
[PubMed - indexed for MEDLINE]
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